Overexpression of the Mitochondrial Malic Enzyme Genes (malC and malD) Improved the Lipid Accumulation in Mucor circinelloides WJ11

Overexpression of the Mitochondrial Malic Enzyme Genes (malC and malD) Improved the Lipid Accumulation in Mucor circinelloides WJ11

Mucor circinelloides serves as a model organism to investigate the lipid metabolism in oleaginous microorganisms. It is considered as an important producer of γ-linolenic acid (GLA) that has vital medicinal benefits. In this study, we used WJ11, a high lipid-producing strain of M. circinelloides (36...

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Bibliographic Details
Main Authors: Abu Bakr Ahmad Fazili, Aabid Manzoor Shah, Mohammed Fahad Albeshr, Tahira Naz, Mohammad Abass Dar, Wu Yang, Victoriano Garre, Khalid Majid Fazili, Eijaz Ahmed Bhat, Yuanda Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Microbiology
Subjects:
lipid accumulation
Mucor circinelloides
oleaginous fungi
malic enzyme
γ-linolenic acid
genetic engineering
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.919364/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.919364/full

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