Aging Aggravates Cachexia in Tumor-Bearing Mice

Aging Aggravates Cachexia in Tumor-Bearing Mice

Background: Cancer is primarily a disease of high age in humans, yet most mouse studies on cancer cachexia are conducted using young adolescent mice. Given that metabolism and muscle function change with age, we hypothesized that aging may affect cachexia progression in mouse models. Methods: We com...

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Bibliographic Details
Main Authors: Julia Geppert, Alina A. Walth, Raúl Terrón Expósito, Doris Kaltenecker, Pauline Morigny, Juliano Machado, Maike Becker, Estefania Simoes, Joanna D. C. C. Lima, Carolin Daniel, Mauricio Berriel Diaz, Stephan Herzig, Marilia Seelaender, Maria Rohm
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
aging
cachexia
cancer
mouse models
Online Access:https://www.mdpi.com/2072-6694/14/1/90

Internet

https://www.mdpi.com/2072-6694/14/1/90

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