Aging Aggravates Cachexia in Tumor-Bearing Mice
Background: Cancer is primarily a disease of high age in humans, yet most mouse studies on cancer cachexia are conducted using young adolescent mice. Given that metabolism and muscle function change with age, we hypothesized that aging may affect cachexia progression in mouse models. Methods: We com...
Main Authors: | Julia Geppert, Alina A. Walth, Raúl Terrón Expósito, Doris Kaltenecker, Pauline Morigny, Juliano Machado, Maike Becker, Estefania Simoes, Joanna D. C. C. Lima, Carolin Daniel, Mauricio Berriel Diaz, Stephan Herzig, Marilia Seelaender, Maria Rohm |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-12-01
|
Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/14/1/90 |
Similar Items
-
Role of Exosomal MicroRNAs and myomiRs in the Development of Cancer Cachexia-Associated Muscle Wasting
by: Rodolfo Marinho, et al.
Published: (2018-01-01) -
Association of circulating PLA2G7 levels with cancer cachexia and assessment of darapladib as a therapy
by: Pauline Morigny, et al.
Published: (2021-10-01) -
Human Cachexia Induces Changes in Mitochondria, Autophagy and Apoptosis in the Skeletal Muscle
by: Gabriela S. de Castro, et al.
Published: (2019-08-01) -
Cancer Cachexia
by: Tanadech Dechaphunkul
Published: (2011-10-01) -
Tumor Microenvironment Autophagic Processes and Cachexia: The Missing Link?
by: Renata de Castro Gonçalves, et al.
Published: (2021-02-01)