Improved l-phenylglycine synthesis by introducing an engineered cofactor self-sufficient system

l-phenylglycine (L-phg) is a valuable non-proteinogenic amino acid used as a precursor to β-lactam antibiotics, antitumor agent taxol and many other pharmaceuticals. L-phg synthesis through microbial bioconversion allows for high enantioselectivity and sustainable production, which will be of great...

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Bibliographic Details
Main Authors: Pengchao Wang, Xiwen Zhang, Yucheng Tao, Xubing Lv, Shengjie Cheng, Chengwei Liu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-03-01
Series:Synthetic and Systems Biotechnology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X21000971