CAR-T therapy followed by allogeneic hematopoietic stem cell transplantation for refractory/relapsed acute B lymphocytic leukemia: Long-term follow-up results

CAR-T therapy followed by allogeneic hematopoietic stem cell transplantation for refractory/relapsed acute B lymphocytic leukemia: Long-term follow-up results

BackgroundPatients with refractory/relapsed (r/r) acute B lymphocytic leukemia (B-ALL) can achieve complete response (CR) after chimeric antigen receptor T-cell (CAR-T) therapy, but recurrence occurs in the short term. To reduce recurrence and improve survival, CAR-T therapy followed by transplantat...

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Bibliographic Details
Main Authors: Zhihui Li, Keyan Yang, Yanzhi Song, Yongqiang Zhao, Fan Wu, Xiaopei Wen, Jing Li, Xianxuan Wang, Teng Xu, Xiaoyu Zheng, Qinglong Zheng, Tong Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Oncology
Subjects:
CAR-T therapy
B-ALL
allo-HSCT
somatic TP53
germline EP300
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1048296/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.1048296/full

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