Inhibition of Plasmid Conjugation in <i>Escherichia coli</i> by Targeting <i>rbsB</i> Gene Using CRISPRi System

Bacterial conjugation constitutes a major horizontal gene transfer mechanism for the dissemination of antibiotic-resistant genes (ARGs) among human pathogens. The spread of ARGs can be halted or diminished by interfering with the conjugation process. In this study, we explored the possibility of usi...

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Bibliographic Details
Main Authors: Yawen Xiao, Yan Zhang, Fengjun Xie, Rikke Heidemann Olsen, Lei Shi, Lili Li
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/13/10585