TNF-α stimulated exosome derived from fibroblast-like synoviocytes isolated from rheumatoid arthritis patients promotes HUVEC migration, invasion and angiogenesis by targeting the miR-200a-3p/KLF6/VEGFA axis

TNF-α stimulated exosome derived from fibroblast-like synoviocytes isolated from rheumatoid arthritis patients promotes HUVEC migration, invasion and angiogenesis by targeting the miR-200a-3p/KLF6/VEGFA axis

AbstractThe pathogenesis of rheumatoid arthritis (RA) is heavily impacted by the inflammation and activation of fibroblast-like synoviocytes (FLS). The objective of this investigation is to clarify the involvement of exosomes derived from FLS stimulated by tumour necrosis factor α (TNF-α) in angioge...

Full description

Bibliographic Details
Main Authors: Bin Zhang, Juanfang Gu, Yiwen Wang, Linfeng Guo, Jiangzhen Xie, Mingfeng Yang
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Autoimmunity
Subjects:
TNF-α
exosomes
angiogenesis
miR-200a-3p
KLF6
Online Access:https://www.tandfonline.com/doi/10.1080/08916934.2023.2282939

Internet

https://www.tandfonline.com/doi/10.1080/08916934.2023.2282939

Similar Items