Phylogeny of Toll-like receptor signaling: adapting the innate response.

The Toll-like receptors represent a largely evolutionarily conserved pathogen recognition machinery responsible for recognition of bacterial, fungal, protozoan, and viral pathogen associated microbial patterns and initiation of inflammatory response. Structurally the Toll-like receptors are comprise...

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Bibliographic Details
Main Authors: Jeffrey M Roach, Luigi Racioppi, Corbin D Jones, Anna Maria Masci
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3543326?pdf=render