mRNA vaccination of rabbits alters the fecundity, but not the attachment, of adult Ixodes scapularis

mRNA vaccination of rabbits alters the fecundity, but not the attachment, of adult Ixodes scapularis

Abstract 19ISP is a nucleoside-modified mRNA-lipid nanoparticle vaccine that targets 19 Ixodes scapularis proteins. We demonstrate that adult I. scapularis have impaired fecundity when allowed to engorge on 19ISP-immunized rabbits. 19ISP, therefore, has the potential to interrupt the tick reproducti...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Jaqueline Matias, Yingjun Cui, Geoffrey E. Lynn, Kathleen DePonte, Emily Mesquita, Hiromi Muramatsu, Mohamad G. Alameh, Garima Dwivedi, Ying K. Tam, Norbert Pardi, Drew Weissman, Erol Fikrig
स्वरूप: लेख
भाषा:English
प्रकाशित: Nature Portfolio 2024-01-01
श्रृंखला:Scientific Reports
ऑनलाइन पहुंच:https://doi.org/10.1038/s41598-023-50389-6

इंटरनेट

https://doi.org/10.1038/s41598-023-50389-6

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