Cu1+, but not Cu2+ is capable of inhibition of AQP4 permeability in an in vitro CHO cell based model

Aquaporin 4 (AQP4) is an important water channel in the central nervous system which is implicated in several neurological disorders. Due to its significance, the identification of molecules which are able to modulate its activity is quite important for potential therapeutic applications. Here we us...

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Bibliographic Details
Main Authors: Arno Vandebroek, Masato Yasui
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Biochemistry and Biophysics Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580821002260