Tannins in Terminalia bellirica inhibits hepatocellular carcinoma growth via re-educating tumor-associated macrophages and restoring CD8+T cell function

Tannins in Terminalia bellirica inhibits hepatocellular carcinoma growth via re-educating tumor-associated macrophages and restoring CD8+T cell function

Tumor-associated macrophages (TAMs) are the major immunosuppressive components infiltrating the tumor microenvironment (TME). Targeting TAMs has emerged as a promising strategy to remodel immunosuppressive TME and enhance T-cell mediated anti-tumor immunity for cancer therapy. In this study, we inve...

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Bibliographic Details
Main Authors: Zihao Chang, Qiunan Zhang, Qian Hu, Yuqi Liu, Lanzhen Zhang, Runping Liu
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Fibrosis
Hepatocellular carcinoma
Immunomodulation
Macrophage polarization
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222009325

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http://www.sciencedirect.com/science/article/pii/S0753332222009325

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