Colorectal cancer patients with low abundance of KRAS mutation may benefit from EGFR antibody therapy.

Epidermal growth factor receptor monoclonal antibody was approved for treatment of metastatic colorectal cancer patients carrying KRAS wild type DNA. However, recent studies showed that patients with KRAS G13D mutation may benefit from EGFR antibody therapy. In this study we tried to explore whether...

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Bibliographic Details
Main Authors: Shaorong Yu, Xia Xiao, Jianwei Lu, Xiaoping Qian, Baorui Liu, Jifeng Feng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3706612?pdf=render