Structural Basis for the Inhibition of Coronaviral Main Proteases by a Benzothiazole-Based Inhibitor

Structural Basis for the Inhibition of Coronaviral Main Proteases by a Benzothiazole-Based Inhibitor

The ongoing spread of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has caused hundreds of millions of cases and millions of victims worldwide with serious consequences to global health and economies. Although many vaccines protecting against SARS-CoV-2 are currently available, consta...

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Bibliographic Details
Main Authors: Xiaohui Hu, Cheng Lin, Qin Xu, Xuelan Zhou, Pei Zeng, Peter J. McCormick, Haihai Jiang, Jian Li, Jin Zhang
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Viruses
Subjects:
coronavirus
main protease
inhibitor
warhead
YH-53
Online Access:https://www.mdpi.com/1999-4915/14/9/2075

Internet

https://www.mdpi.com/1999-4915/14/9/2075

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