Reactive oxygen species trigger NF-κB-mediated NLRP3 inflammasome activation involvement in low-dose CdTe QDs exposure-induced hepatotoxicity

Reactive oxygen species trigger NF-κB-mediated NLRP3 inflammasome activation involvement in low-dose CdTe QDs exposure-induced hepatotoxicity

Cadmium telluride (CdTe) quantum dots (QDs) can be employed as imaging and drug delivery tools; however, the toxic effects and mechanisms of low-dose exposure are unclear. Therefore, this pioneering study focused on hepatic macrophages (Kupffer cells, KCs) and explored the potential damage process i...

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Bibliographic Details
Main Authors: Yanting Pang, Daming Wu, Ying Ma, Yuna Cao, Qing Liu, Meng Tang, Yuepu Pu, Ting Zhang
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Redox Biology
Subjects:
Cd telluride quantum dots
Low-dose exposure
Reactive oxygen species
Hepatic macrophages (Kupffer cell)
NLRP3 inflammasome
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231721003177

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http://www.sciencedirect.com/science/article/pii/S2213231721003177

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