Binding Folate Receptor Alpha Autoantibody Is a Biomarker for Leucovorin Treatment Response in Autism Spectrum Disorder

Binding Folate Receptor Alpha Autoantibody Is a Biomarker for Leucovorin Treatment Response in Autism Spectrum Disorder

Autism spectrum disorder (ASD) affects up to 1 in 36 children in the United States. It is a heterogeneous neurodevelopmental disorder with life-long consequences. Patients with ASD and folate pathway abnormalities have demonstrated improved symptoms after treatment with leucovorin (folinic acid), a...

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Bibliographic Details
Main Authors: Richard E. Frye, Patrick J. McCarty, Brianna A. Werner, Adrienne C. Scheck, Heidi L. Collins, Steven J. Adelman, Daniel A. Rossignol, Edward V. Quadros
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Journal of Personalized Medicine
Subjects:
autism spectrum disorder
folate receptor alpha
soluble folate binding proteins
folinic acid
leucovorin
Online Access:https://www.mdpi.com/2075-4426/14/1/62

Internet

https://www.mdpi.com/2075-4426/14/1/62

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