Universally valid reduction of multiscale stochastic biochemical systems using simple non-elementary propensities.

Biochemical systems consist of numerous elementary reactions governed by the law of mass action. However, experimentally characterizing all the elementary reactions is nearly impossible. Thus, over a century, their deterministic models that typically contain rapid reversible bindings have been simpl...

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Bibliographic Details
Main Authors: Yun Min Song, Hyukpyo Hong, Jae Kyoung Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-10-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1008952