Extracellular vesicles in cardiac repair and regeneration: Beyond stem-cell-based approaches

The adult human heart poorly regenerate after injury due to the low self-renewal capability retained by adult cardiomyocytes. In the last two decades, several clinical studies have reported the ability of stem cells to induce cardiac regeneration. However, low cell integration and survival into the...

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Bibliographic Details
Main Authors: Saveria Femminò, Filippo Bonelli, Maria Felice Brizzi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.996887/full