The loss of β adrenergic receptor mediated release potentiation in a mouse model of fragile X syndrome

The loss of β adrenergic receptor mediated release potentiation in a mouse model of fragile X syndrome

In fragile X syndrome, the absence of Fragile X Mental Retardation Protein (FMRP) is known to alter postsynaptic function, although alterations in presynaptic function also occur. We found that the potentiation of glutamate release induced by the β adrenergic receptor (βAR) agonist isoproterenol is...

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Bibliographic Details
Main Authors: Nuria García-Font, Ricardo Martín, Magdalena Torres, María Jesus Oset-Gasque, José Sánchez-Prieto
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Neurobiology of Disease
Subjects:
β adrenergic receptors
Glutamate release
cAMP
Cerebrocortical nerve terminals
Fmr1 KO mice
Fragile X syndrome
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996119301330

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http://www.sciencedirect.com/science/article/pii/S0969996119301330

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