The hierarchical assembly of septins revealed by high-speed AFM

Septins are GTP-binding proteins involved in diverse cellular processes including division, polarity maintenance and membrane remodeling. Here authors use high-speed atomic force microscopy to show that assembly of septin filaments is a diffusion-driven process, while septin assembly into higher-ord...

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Bibliographic Details
Main Authors: Fang Jiao, Kevin S. Cannon, Yi-Chih Lin, Amy S. Gladfelter, Simon Scheuring
Format: Article
Language:English
Published: Nature Portfolio 2020-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18778-x