Intracerebroventricular Ghrelin Administration Increases Depressive-Like Behavior in Male Juvenile Rats

Major depressive disorder (MDD) is arguably the largest contributor to the global disease and disability burden, but very few treatment options exist for juvenile MDD patients. Ghrelin is the principal hunger-stimulating peptide, and it has also been shown to reduce depressive-like symptoms in adult...

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Bibliographic Details
Main Authors: Thomas M. Jackson, Tim D. Ostrowski, David S. Middlemas
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnbeh.2019.00077/full