Antibodies targeting Candida albicans Als3 and Hyr1 antigens protect neonatal mice from candidiasis

Antibodies targeting Candida albicans Als3 and Hyr1 antigens protect neonatal mice from candidiasis

Pre-term infants in neonatal intensive care units are vulnerable to fungal sepsis. In this patient population, Candida albicans remains the predominant fungal pathogen causing high morbidity and mortality, despite antifungal therapy. Thus, new preventative/therapeutic strategies against neonatal can...

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Bibliographic Details
Main Authors: Shakti Singh, Sunna Nabeela, Ashley Barbarino, Ashraf S. Ibrahim, Priya Uppuluri
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
neonates
antibodies
Als3
Hyr1
neonatal candidiasis
vaccine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.925821/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.925821/full

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