Preparation of Glutathione-Responsive Paclitaxel Prodrug Based on Endogenous Molecule of L-Glutathione Oxidized for Cancer Therapy

Preparation of Glutathione-Responsive Paclitaxel Prodrug Based on Endogenous Molecule of L-Glutathione Oxidized for Cancer Therapy

Using an endogenous carrier is the best method to address the biocompatibility of carriers in the drug delivery field. Herein, we prepared a glutathione-responsive paclitaxel prodrug micelle based on an endogenous molecule of L-glutathione oxidized (GSSG) for cancer therapy using one-pot synthesis....

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Bibliographic Details
Main Authors: Xiao Duan, Qiang Wang, Yue Wang, Xinping Liu, Manman Lu, Zhifang Li, Xuelian Jiang, Jingquan Ji
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Pharmaceutics
Subjects:
glutathione responsiveness
paclitaxel prodrug
micelles
antitumor
Online Access:https://www.mdpi.com/1999-4923/16/9/1178

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https://www.mdpi.com/1999-4923/16/9/1178

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