Tramadol’s Inhibitory Effects on Sexual Behavior: Pharmacological Studies in Serotonin Transporter Knockout Rats

Tramadol’s Inhibitory Effects on Sexual Behavior: Pharmacological Studies in Serotonin Transporter Knockout Rats

Tramadol is an effective pharmacological intervention in human premature ejaculation (PE). To investigate whether the inhibitory action of tramadol is primarily caused by its selective serotonin reuptake inhibitory (SSRI) effects we tested the dose–response effects of tramadol on sexual behavior in...

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Bibliographic Details
Main Authors: Diana C. Esquivel-Franco, Berend Olivier, Marcel D. Waldinger, Gabriel Gutiérrez-Ospina, Jocelien D. A. Olivier
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Pharmacology
Subjects:
SSRI
sexual behavior
tramadol
rat
5-HT1A receptor
μ-opioid receptor
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00676/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00676/full

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