Permeation of Molecules through Astroglial Connexin 43 Hemichannels Is Modulated by Cytokines with Parameters Depending on the Permeant Species

Permeation of Molecules through Astroglial Connexin 43 Hemichannels Is Modulated by Cytokines with Parameters Depending on the Permeant Species

Recent studies indicate that connexin hemichannels do not act as freely permeable non-selective pores, but they select permeants in an isoform-specific manner with cooperative, competitive and saturable kinetics. The aim of this study was to investigate whether the treatment with a mixture of IL-1β...

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Bibliographic Details
Main Authors: Juan C. Sáez, Aníbal A. Vargas, Diego E. Hernández, Fernando C. Ortiz, Christian Giaume, Juan A. Orellana
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
connexons
dyes
permeability tracers
permeation
TNF-α
IL-1β
Online Access:https://www.mdpi.com/1422-0067/21/11/3970

Internet

https://www.mdpi.com/1422-0067/21/11/3970

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