Modeling antibody dynamics following herpes zoster indicates that higher varicella-zoster virus viremia generates more VZV-specific antibodies

Modeling antibody dynamics following herpes zoster indicates that higher varicella-zoster virus viremia generates more VZV-specific antibodies

IntroductionStudying antibody dynamics following re-exposure to infection and/or vaccination is crucial for a better understanding of fundamental immunological processes, vaccine development, and health policy research.MethodsWe adopted a nonlinear mixed modeling approach based on ordinary different...

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Bibliographic Details
Main Authors: Hajar Besbassi, Irene Garcia-Fogeda, Mark Quinlivan, Judy Breuer, Steven Abrams, Niel Hens, Benson Ogunjimi, Philippe Beutels
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
Subjects:
varicella zoster virus
herpes zoster
antibody levels
ordinary differential equations
nonlinear mixed-effects models
mathematical modeling
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1104605/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1104605/full

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