IgA Immune Complexes Induce Osteoclast-Mediated Bone Resorption

IgA Immune Complexes Induce Osteoclast-Mediated Bone Resorption

ObjectiveAutoantibodies are detected in most patients with rheumatoid arthritis (RA) and can be of the IgM, IgG or IgA subclass. Correlations between IgA autoantibodies and more severe disease activity have been previously reported, but the functional role of IgA autoantibodies in the pathogenesis o...

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Bibliographic Details
Main Authors: Annelot C. Breedveld, Melissa M. J. van Gool, Myrthe A. M. van Delft, Conny J. van der Laken, Teun J. de Vries, Ineke D. C. Jansen, Marjolein van Egmond
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
ACPA
autoantibodies
bone resorption
IgA
osteoclast
rheumatoid arthritis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.651049/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.651049/full

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