Derivatives of Salarin A, Salarin C and Tulearin A—Fascaplysinopsis sp. Metabolites

Derivatives of Salarin A, Salarin C and Tulearin A—Fascaplysinopsis sp. Metabolites

Derivatives of salarin A, salarin C and tulearin A, three new cytotoxic sponge derived nitrogenous macrolides, were prepared and bio-evaluated as inhibitors of K562 leukemia cells. Interesting preliminary SAR (structure activity relationship) information was obtained from the products. The most sens...

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Bibliographic Details
Main Authors: Nathalie Ben-Califa, Drorit Neumann, Maurice Aknin, Ashgan Bishara, Lee Goren Zur, Yoel Kashman
Format: Article
Language:English
Published: MDPI AG 2013-11-01
Series:Marine Drugs
Subjects:
salarins
tulearins
Fascaplysinopsis sp.
sponge
nitrogenous macrolide
leukemia cells
Online Access:http://www.mdpi.com/1660-3397/11/11/4487

Internet

http://www.mdpi.com/1660-3397/11/11/4487

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