Generation of three iPSC lines from dilated cardiomyopathy patients carrying a pathogenic LMNA variant

LMNA-related dilated cardiomyopathy (DCM) is caused by pathogenic variants in LMNA and is characterized by left ventricular enlargement, reduced systolic function, and arrhythmia. Here, we generated three human induced pluripotent stem cell (iPSC) lines from peripheral blood mononuclear cells (PBMCs...

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Bibliographic Details
Main Authors: Chelsea Lee, Sangkyun Cho, Celine Lai, Sushma Shenoy, Randall Vagelos, Joseph C. Wu
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506121004852