Regulation of Nuclear Receptor Nur77 by miR-124.

The nuclear receptor Nur77 is commonly upregulated in adult cancers and has oncogenic functions. Nur77 is an immediate-early response gene that acts as a transcription factor to promote proliferation and protect cells from apoptosis. Conversely, Nur77 can translocate to the mitochondria and induce a...

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Bibliografische gegevens
Hoofdauteurs: Alexa Tenga, Jordan A Beard, Apana Takwi, Yue-Ming Wang, Taosheng Chen
Formaat: Artikel
Taal:English
Gepubliceerd in: Public Library of Science (PLoS) 2016-01-01
Reeks:PLoS ONE
Online toegang:http://europepmc.org/articles/PMC4739595?pdf=render