Immunoprofiles and DNA Methylation of Inflammatory Marker Genes in Ulcerative Colitis-Associated Colorectal Tumorigenesis

Immunoprofiles and DNA Methylation of Inflammatory Marker Genes in Ulcerative Colitis-Associated Colorectal Tumorigenesis

Immunological and epigenetic changes are interconnected and contribute to tumorigenesis. We determined the immunoprofiles and promoter methylation of inflammation-related genes for colitis-associated colorectal carcinomas (CA-CRC). The results were compared with Lynch syndrome (LS)-associated colore...

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Bibliographic Details
Main Authors: Satu Mäki-Nevala, Sanjeevi Ukwattage, Erkki-Ville Wirta, Maarit Ahtiainen, Ari Ristimäki, Toni T. Seppälä, Anna Lepistö, Jukka-Pekka Mecklin, Päivi Peltomäki
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biomolecules
Subjects:
Lynch syndrome
ulcerative colitis
colon cancer
immune cell score
DNA methylation
inflammation-associated genes
Online Access:https://www.mdpi.com/2218-273X/11/10/1440

Internet

https://www.mdpi.com/2218-273X/11/10/1440

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