Development of Machine Learning Models for Accurately Predicting and Ranking the Activity of Lead Molecules to Inhibit PRC2 Dependent Cancer

Disruption of epigenetic processes to eradicate tumor cells is among the most promising interventions for cancer control. EZH2 (Enhancer of zeste homolog 2), a catalytic component of polycomb repressive complex 2 (PRC2), methylates lysine 27 of histone H3 to promote transcriptional silencing and is...

詳細記述

書誌詳細
主要な著者: Danishuddin, Vikas Kumar, Shraddha Parate, Ashutosh Bahuguna, Gihwan Lee, Myeong Ok Kim, Keun Woo Lee
フォーマット: 論文
言語:English
出版事項: MDPI AG 2021-07-01
シリーズ:Pharmaceuticals
主題:
オンライン・アクセス:https://www.mdpi.com/1424-8247/14/7/699