Influence of Complexation of Thiosemicarbazone Derivatives with Cu (II) Ions on Their Antitumor Activity against Melanoma Cells

Influence of Complexation of Thiosemicarbazone Derivatives with Cu (II) Ions on Their Antitumor Activity against Melanoma Cells

A series of thiosemicarbazone derivatives was prepared and their anti-tumor activity in vitro was tested. The X-ray investigation performed for compounds T2, T3 and T5 confirmed the synthesis pathway and assumed molecular structures of analyzed thiosemicarbazones. The conformational preferences of t...

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Bibliographic Details
Main Authors: Monika Pitucha, Agnieszka Korga-Plewko, Agnieszka Czylkowska, Bartłomiej Rogalewicz, Monika Drozd, Magdalena Iwan, Joanna Kubik, Ewelina Humeniuk, Grzegorz Adamczuk, Zbigniew Karczmarzyk, Emilia Fornal, Waldemar Wysocki, Paulina Bartnik
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
synthesis
thiosemicarbazone
X-ray investigation
copper(II) complex
TG-DTG techniques
melanoma
Online Access:https://www.mdpi.com/1422-0067/22/6/3104

Internet

https://www.mdpi.com/1422-0067/22/6/3104

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