Synaptic density in aging mice measured by [18F]SynVesT-1 PET

Synaptic density in aging mice measured by [18F]SynVesT-1 PET

Synaptic alterations in certain brain structures are related to cognitive decline in neurodegeneration and in aging. Synaptic loss in many neurodegenerative diseases can be visualized by positron emission tomography (PET) imaging of synaptic vesicle glycoprotein 2A (SV2A). However, the use of SV2A P...

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Bibliographic Details
Main Authors: Mengfei Xiong, Sahar Roshanbin, Dag Sehlin, Hanne D. Hansen, Gitte M. Knudsen, Johanna Rokka, Jonas Eriksson, Stina Syvänen
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:NeuroImage
Subjects:
Synaptic density
Aging
Positron emission tomography (PET)
Mice
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811923003816

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http://www.sciencedirect.com/science/article/pii/S1053811923003816

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