DJ-1 promotes osteosarcoma progression through activating CDK4/RB/E2F1 signaling pathway

DJ-1 promotes osteosarcoma progression through activating CDK4/RB/E2F1 signaling pathway

Osteosarcoma (OS) is a primary malignant tumor of the bone characterized by poor prognosis due to chemotherapy resistance and high recurrence rates. DJ-1 (PARK7) is known as an oncogene and its abnormal expression is related to the poor prognosis of various types of malignant tumors. It was found in...

Full description

Bibliographic Details
Main Authors: Zhitao Han, Lining Wang, Dongshuo Wang, Luosheng Zhang, Yifeng Bi, Xinlei Zheng, Weibo Liu, Guangjian Bai, Zhenhua Wang, Wei Wan, Yong Ma, Xiaopan Cai, Tielong Liu, Qi Jia
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Oncology
Subjects:
DJ-1 (PARK7)
cdk4
RB
E2F1
osteosarcoma (OS)
target therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1036401/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.1036401/full

Similar Items