Enhancing Oral Bioavailability of Apigenin Using a Bioactive Self-Nanoemulsifying Drug Delivery System (Bio-SNEDDS): In Vitro, In Vivo and Stability Evaluations

Enhancing Oral Bioavailability of Apigenin Using a Bioactive Self-Nanoemulsifying Drug Delivery System (Bio-SNEDDS): In Vitro, In Vivo and Stability Evaluations

Apigenin (APG) is a very well-known flavonoid for its anti-inflammatory and anticancer properties. The purpose of this study is to improve the solubility and bioavailability of APG using a stable bioactive self-nanoemulsifying drug delivery system (Bio-SNEDDS). APG was incorporated in an oil phase c...

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Bibliographic Details
Main Authors: Mohsin Kazi, Abdullah Alhajri, Sultan M. Alshehri, Ehab M. Elzayat, Osaid T. Al Meanazel, Faiyaz Shakeel, Omar Noman, Mohammad A. Altamimi, Fars K. Alanazi
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Pharmaceutics
Subjects:
bioactive self-nanoemulsifying drug delivery system (Bio-SNEDDS)
apigenin
solubility improvement
oral bioavailability enhancement
Online Access:https://www.mdpi.com/1999-4923/12/8/749

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https://www.mdpi.com/1999-4923/12/8/749

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