Non-catalytic mechanisms of KMT5C regulating hepatic gluconeogenesis

Non-catalytic mechanisms of KMT5C regulating hepatic gluconeogenesis

Abstract Lysine methyltransferase KMT5C catalyzes deposition of trimethylation on histone H4 lysine 20 (H4K20me3), an epigenetic marker usually associated with gene repression and maintenance of heterochromatin. KMT5C is widely expressed in a variety of tissues, however, its functional role in liver...

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Bibliographic Details
Main Authors: Qingwen Zhao, Xuan Cui, Qi Zhu, Feiyan Li, Ran Bao, Ting Shi, Haojie Liu, Wenjing Lv, Yingjiang Xu, Yue Gao, Qi-Qun Tang, Min Zhang, Dongning Pan
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56696-y

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https://doi.org/10.1038/s41467-025-56696-y

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