Spotlights on ubiquitin-specific protease 12 (USP12) in diseases: from multifaceted roles to pathophysiological mechanisms

Spotlights on ubiquitin-specific protease 12 (USP12) in diseases: from multifaceted roles to pathophysiological mechanisms

Abstract Ubiquitination is one of the most significant post-translational modifications that regulate almost all physiological processes like cell proliferation, autophagy, apoptosis, and cell cycle progression. Contrary to ubiquitination, deubiquitination removes ubiquitin from targeted protein to...

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Bibliographic Details
Main Authors: Kaiyi Niu, Yanlong Shi, Qingpeng Lv, Yizhu Wang, Jiping Chen, Wenning Zhang, Kung Feng, Yewei Zhang
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Journal of Translational Medicine
Subjects:
USP12
Deubiquitination
Tumorigenesis
Immune response
Cancer
Online Access:https://doi.org/10.1186/s12967-023-04540-6

Internet

https://doi.org/10.1186/s12967-023-04540-6

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