Single-cell transcriptomic atlas of lung microvascular regeneration after targeted endothelial cell ablation

Single-cell transcriptomic atlas of lung microvascular regeneration after targeted endothelial cell ablation

We sought to define the mechanism underlying lung microvascular regeneration in a model of severe acute lung injury (ALI) induced by selective lung endothelial cell ablation. Intratracheal instillation of DT in transgenic mice expressing human diphtheria toxin (DT) receptor targeted to ECs resulted...

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Bibliographic Details
Main Authors: Rafael Soares Godoy, Nicholas D Cober, David P Cook, Emma McCourt, Yupu Deng, Liyuan Wang, Kenny Schlosser, Katelynn Rowe, Duncan J Stewart
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-04-01
Series:eLife
Subjects:
angiogenesis
endothelial cells
pulmonary biology
stem cells
apelin
Online Access:https://elifesciences.org/articles/80900

Internet

https://elifesciences.org/articles/80900

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