Regulatory pattern of abnormal promoter CpG island methylation in the glioblastoma multiforme classification

Regulatory pattern of abnormal promoter CpG island methylation in the glioblastoma multiforme classification

Glioblastoma (GBM) is characterized by extensive genetic and phenotypic heterogeneity. However, it remains unexplored primarily how CpG island methylation abnormalities in promoter mediate glioblastoma typing. First, we presented a multi-omics scale map between glioblastoma sample clusters construct...

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Bibliographic Details
Main Authors: Rendong Wang, Lei Zhao, Shijia Wang, Xiaoxiao Zhao, Chuanyu Liang, Pei Wang, Dongguo Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Genetics
Subjects:
glioblastoma 1
subtype classification 2
CpG island 3
DNA methylation 4
tumor microenviroment 5
single-cell RNA sequencing 6
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.989985/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.989985/full

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