A Novel High-Potency Tetanus Vaccine

ABSTRACT Chemically inactivated tetanus toxoid (CITT) is clinically effective and widely used. However, CITT is a crude nonmalleable vaccine that contains hundreds of Clostridium tetani proteins, and the active component is present in variable and sometimes minor percentages of vaccine mass. Recombi...

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Bibliographic Details
Main Authors: Amanda Przedpelski, William H. Tepp, Sabine Pellett, Eric A. Johnson, Joseph T. Barbieri
Format: Article
Language:English
Published: American Society for Microbiology 2020-08-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.01668-20