Microbial antigens-loaded myeloma cells enhance Th2 cell proliferation and myeloma clonogenicity via Th2–myeloma cell interaction

Microbial antigens-loaded myeloma cells enhance Th2 cell proliferation and myeloma clonogenicity via Th2–myeloma cell interaction

Abstract Background Myeloma cells retain B cell functions, considered to be potential antigen presenting cells, yet there is little information regarding promoting Th2 cell proliferation or the direct effects to myeloma on the Th2 cells stimulated by microbial antigens-loaded myeloma cells. Methods...

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Bibliographic Details
Main Authors: Faqing Tian, Bo Lu, Ziren Chen, Junru Liu, Delan Ji, Juheng Li, Meiqin Tang, Wei Zhu, Juan Li
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Cancer
Subjects:
Myeloma
Microbial antigen
Antigen presenting cells
Th2 cell
Clonogenicity
MHC- II restriction
Online Access:https://doi.org/10.1186/s12885-019-6469-4

Internet

https://doi.org/10.1186/s12885-019-6469-4

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