Nuclear pore protein POM121 regulates subcellular localization and transcriptional activity of PPARγ

Nuclear pore protein POM121 regulates subcellular localization and transcriptional activity of PPARγ

Abstract Manipulation of the subcellular localization of transcription factors by preventing their shuttling via the nuclear pore complex (NPC) emerges as a novel therapeutic strategy against cancer. One transmembrane component of the NPC is POM121, encoded by a tandem gene locus POM121A/C on chromo...

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Bibliographic Details
Main Authors: Yanxiong Yu, Mohammad S. Farooq, Sabine Eberhart Meessen, Yidan Jiang, Dominik Kato, Tianzuo Zhan, Christel Weiss, Rony Seger, Wei Kang, Xiang Zhang, Jun Yu, Matthias P. A. Ebert, Elke Burgermeister
Format: Article
Language:English
Published: Nature Publishing Group 2024-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06371-1

Internet

https://doi.org/10.1038/s41419-023-06371-1

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