Alveolar type I cells can give rise to KRAS-induced lung adenocarcinoma

Summary: Lung adenocarcinoma (LUAD) is the most prevalent subtype of lung cancer and presents clinically with a high degree of biological heterogeneity and distinct clinical outcomes. The current paradigm of LUAD etiology posits alveolar epithelial type II (AT2) cells as the primary cell of origin,...

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Detalles Bibliográficos
Main Authors: Minxiao Yang, Hua Shen, Per Flodby, Michael D. Koss, Rania Bassiouni, Yixin Liu, Tea Jashashvili, Aaron Neely, Ezuka Ogbolu, Jonathan Castillo, Theresa Ryan Stueve, Daniel J. Mullen, Amy L. Ryan, John Carpten, Alessandra Castaldi, W. Dean Wallace, Beiyun Zhou, Zea Borok, Crystal N. Marconett
Formato: Artigo
Idioma:English
Publicado: Elsevier 2023-12-01
Series:Cell Reports
Subjects:
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2211124723012986