Endocytosis of the IFNAR1 chain of Type 1 interferon receptor is regulated by diverse E2 ubiquitin conjugation enzymes

Endocytosis of the IFNAR1 chain of Type 1 interferon receptor is regulated by diverse E2 ubiquitin conjugation enzymes

Ubiquitination of signaling receptors triggers their endocytosis to restrict the extent of cell signaling. Type 1 interferon (IFN1) eliminates its receptor from cell surface via stimulating the ubiquitination of its IFNAR1 chain. While it was suggested that this ubiquitination aids IFNAR1internaliza...

Full description

Bibliographic Details
Format: Article
Language:Russian
Published: ABV-press 2015-06-01
Series:Успехи молекулярной онкологии
Subjects:
ifnar
interferon
receptor
ubiquitin
endocytosis
e2
Online Access:https://umo.abvpress.ru/jour/article/view/28

Internet

https://umo.abvpress.ru/jour/article/view/28

Similar Items