The evolution of two-component systems in bacteria reveals different strategies for niche adaptation.

Two-component systems including histidine protein kinases represent the primary signal transduction paradigm in prokaryotic organisms. To understand how these systems adapt to allow organisms to detect niche-specific signals, we analyzed the phylogenetic distribution of nearly 5,000 histidine protei...

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Bibliographic Details
Main Authors: Eric Alm, Katherine Huang, Adam Arkin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-11-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.0020143