Diabetes type, hemoglobin A1C biomarker and control as predictors for dental treatment needs

Introduction: The goal of this study was to test the impact of both diabetes type and control via the hemoglobin A1C biomarker on oral health outcomes. Materials & Methods: In this observational study, data were extracted from the University of Pittsburgh Dental Registry and DNA Repository and a...

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Main Authors: Lily A. Hartsock, Alexandre R. Vieira
Format: Article
Language:English
Published: Babol University of Medical Sciences 2021-03-01
Series:Caspian journal of dental research
Subjects:
Online Access:http://cjdr.ir/article-1-303-en.html
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author Lily A. Hartsock
Alexandre R. Vieira
author_facet Lily A. Hartsock
Alexandre R. Vieira
author_sort Lily A. Hartsock
collection DOAJ
description Introduction: The goal of this study was to test the impact of both diabetes type and control via the hemoglobin A1C biomarker on oral health outcomes. Materials & Methods: In this observational study, data were extracted from the University of Pittsburgh Dental Registry and DNA Repository and analyzed. From 6,026 subjects, 414 ones with a diagnosis of diabetes were matched by sex, age and ethnicity with 414 individuals without diabetes. A number of statistical approaches (chi-square, Fisher’s exact, Student’s t, Wilcox, and Mann Whitney tests) were used and all comparisons were set with an alpha of 0.05. Results: Patients with type 1 diabetes experienced xerostomia more often compared to non-diabetic matched pairs (p=0.02). Patients with diabetes (n=414) experienced temporomandibular joint (TMJ) discomfort more often than their non-diabetic matched pairs, as did type 1 diabetic patients alone, in comparison to both their matched pairs and type 2 diabetic patients (p=0.01, p=0.004, and p=0.02, respectively). Among patients grouped by diabetic control, all patients reporting control (n=39) experienced xerostomia more often than their non-diabetic matched pairs (p=0.05). Patients in poor diabetic control experienced restoration failure more often than patients in good control (p=0.04). The experience of restoration failure was no different between patients in good diabetic control and their matched controls (p=0.26). The number of restoration failures was higher in patients in poor control, as compared to their matched non-diabetic controls (p=0.03). Conclusion: Patients with diabetes experienced xerostomia but not necessarily more severe caries experience, and may be protected from TMJ discomfort. Patients in good control of their diabetes were at no greater risk for restoration failure as compared to non-diabetic patients; however, the patients in poor control were at higher risk for failed restorations.
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spelling doaj.art-6bf2b7d67fed46c4bfdbb03969705fca2022-12-21T22:20:31ZengBabol University of Medical SciencesCaspian journal of dental research2251-98902322-23952021-03-01101818Diabetes type, hemoglobin A1C biomarker and control as predictors for dental treatment needsLily A. Hartsock0Alexandre R. Vieira1 ,Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA. ,Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA. Introduction: The goal of this study was to test the impact of both diabetes type and control via the hemoglobin A1C biomarker on oral health outcomes. Materials & Methods: In this observational study, data were extracted from the University of Pittsburgh Dental Registry and DNA Repository and analyzed. From 6,026 subjects, 414 ones with a diagnosis of diabetes were matched by sex, age and ethnicity with 414 individuals without diabetes. A number of statistical approaches (chi-square, Fisher’s exact, Student’s t, Wilcox, and Mann Whitney tests) were used and all comparisons were set with an alpha of 0.05. Results: Patients with type 1 diabetes experienced xerostomia more often compared to non-diabetic matched pairs (p=0.02). Patients with diabetes (n=414) experienced temporomandibular joint (TMJ) discomfort more often than their non-diabetic matched pairs, as did type 1 diabetic patients alone, in comparison to both their matched pairs and type 2 diabetic patients (p=0.01, p=0.004, and p=0.02, respectively). Among patients grouped by diabetic control, all patients reporting control (n=39) experienced xerostomia more often than their non-diabetic matched pairs (p=0.05). Patients in poor diabetic control experienced restoration failure more often than patients in good control (p=0.04). The experience of restoration failure was no different between patients in good diabetic control and their matched controls (p=0.26). The number of restoration failures was higher in patients in poor control, as compared to their matched non-diabetic controls (p=0.03). Conclusion: Patients with diabetes experienced xerostomia but not necessarily more severe caries experience, and may be protected from TMJ discomfort. Patients in good control of their diabetes were at no greater risk for restoration failure as compared to non-diabetic patients; however, the patients in poor control were at higher risk for failed restorations.http://cjdr.ir/article-1-303-en.htmldental cariesperiodontitisdental amalgamdental restoration failure
spellingShingle Lily A. Hartsock
Alexandre R. Vieira
Diabetes type, hemoglobin A1C biomarker and control as predictors for dental treatment needs
Caspian journal of dental research
dental caries
periodontitis
dental amalgam
dental restoration failure
title Diabetes type, hemoglobin A1C biomarker and control as predictors for dental treatment needs
title_full Diabetes type, hemoglobin A1C biomarker and control as predictors for dental treatment needs
title_fullStr Diabetes type, hemoglobin A1C biomarker and control as predictors for dental treatment needs
title_full_unstemmed Diabetes type, hemoglobin A1C biomarker and control as predictors for dental treatment needs
title_short Diabetes type, hemoglobin A1C biomarker and control as predictors for dental treatment needs
title_sort diabetes type hemoglobin a1c biomarker and control as predictors for dental treatment needs
topic dental caries
periodontitis
dental amalgam
dental restoration failure
url http://cjdr.ir/article-1-303-en.html
work_keys_str_mv AT lilyahartsock diabetestypehemoglobina1cbiomarkerandcontrolaspredictorsfordentaltreatmentneeds
AT alexandrervieira diabetestypehemoglobina1cbiomarkerandcontrolaspredictorsfordentaltreatmentneeds