The Ubiquitin Ligase (E3) Psh1p Is Required for Proper Segregation of both Centromeric and Two-Micron Plasmids in Saccharomyces cerevisiae

The Ubiquitin Ligase (E3) Psh1p Is Required for Proper Segregation of both Centromeric and Two-Micron Plasmids in Saccharomyces cerevisiae

Protein degradation by the ubiquitin-proteasome system is essential to many processes. We sought to assess its involvement in the turnover of mitochondrial proteins in Saccharomyces cerevisiae. We find that deletion of a specific ubiquitin ligase (E3), Psh1p, increases the abundance of a temperature...

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Bibliographic Details
Main Authors: Meredith B. Metzger, Jessica L. Scales, Mitchell F. Dunklebarger, Allan M. Weissman
Format: Article
Language:English
Published: Oxford University Press 2017-11-01
Series:G3: Genes, Genomes, Genetics
Subjects:
ubiquitination
Cse4p
plasmid missegregation
CEN plasmid
2 μm plasmid
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.117.300227

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http://g3journal.org/lookup/doi/10.1534/g3.117.300227

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