Associations of genome-wide and regional autozygosity with 96 complex traits in old order Amish
Abstract Background: Autozygosity, the proportion of the genome that is homozygous by descent, has been associated with variation in multiple health-related traits impacting evolutionary fitness. Autozygosity (FROH) is typically measured from runs of homozygosity (ROHs) that arise when identical-by-...
Autori principali: | , , , , , , |
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Natura: | Articolo |
Lingua: | English |
Pubblicazione: |
BMC
2023-03-01
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Serie: | BMC Genomics |
Soggetti: | |
Accesso online: | https://doi.org/10.1186/s12864-023-09208-5 |