Mesenchymal Stromal Cells: Role in the BM Niche and in the Support of Hematopoietic Stem Cell Transplantation
Abstract. Mesenchymal stromal cells (MSCs) are key elements in the bone marrow (BM) niche where they interact with hematopoietic stem progenitor cells (HSPCs) by offering physical support and secreting soluble factors, which control HSPC maintenance and fate. Although necessary for their maintenance...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2018-12-01
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Series: | HemaSphere |
Online Access: | http://journals.lww.com/10.1097/HS9.0000000000000151 |