Inhibition of adenosine A1 receptors abolished the nutritional ketosis-evoked delay in the onset of isoflurane-induced anesthesia in Wistar Albino Glaxo Rijswijk rats

Abstract Background It has been demonstrated that administration of exogenous ketone supplement ketone salt (KS) and ketone ester (KE) increased blood ketone level and delayed the onset of isoflurane-induced anesthesia in different rodent models, such as Wistar Albino Glaxo Rijswijk (WAG/Rij) rats....

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Bibliographic Details
Main Authors: Zsolt Kovács, Brigitta Brunner, Dominic P. D’Agostino, Csilla Ari
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Anesthesiology
Subjects:
Online Access:https://doi.org/10.1186/s12871-020-0943-z